The suppression of important WT1 isoform-mediated transcriptional activation by Ex4a(+) WT1 is likely to be prolonged to other immediate transcriptional targets also as Bcl-xL and Bcl-2. Considering that various other genes responsible for anti-apoptosis these as BFL-1 and c-myc are actually also recognized as immediate transcriptional targets of important WT1 isoforms [16, 17], Ex4a(+)WT1-induced
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