Moreover, the Ex4a(+)WT1 isoform and total WT1 isoforms which includes each Ex4a(+) and major WT1 isoforms had been quantified by quantitative real-time PCR (Fig 6C). The outcome confirmed that Ex4a(+)WT1 isoform was elevated and important WT1 isoforms ended up reduced by apoptosis. When etoposide was applied being an apoptosis inducer, the comparable effects were attained (details not proven).Mor