These success indicated that greater expression of the Ex4a(+)WT1 isoform might lead to the induction of apoptosis. In addition, to examine the results on the endogenous Ex4a(+)WT1 isoform on Dox-induced apoptosis, K562 cells were being transfected with possibly of two distinct WT1 Ex4a-specific siRNAs (si-4a-1 and si-4a-2) or handle siRNA (si-control) for twenty-four h, treated with Dox for twelv